> Vaccino per the human papillomavirus (verruche umane)

it is expected that the vaccine can be is offered free of charge from public facilities from 2008 to all the girls at the age of 12 years.

In Italy, the cancer of the neck of the uterus, affecting approximately 3500 women per year: the impact of the più high is around 45 years of age, while it is virtually absent under 25 years old.

Today, the best weapon to combat this cancer is the Pap Test (known as “smear”), an examination is simple and harmless, that allows to identify the presence of lesions is also very small and to treat them promptly before they turn into cancer.

In the different Italian regions are active prevention programs (screening) for all women of età between 25 and 64 years of age: these women are being invited by the USL to make a Pap Test completely free of charge every 3 years.

What type of vaccine will beà the proposed?

this Is a vaccine against the papilloma virus (HPV). Of this there are over 120 different types (strains), but the vast majority do not cause injury, and tumors. The vaccine put on the market is directed against 4 strains of the virus: HPV 16, HPV 18, HPV 11, HPV 6. Two of these (HPV 16 and 18) are more frequently related to the tumor lesions and are responsible for only 70% of the cases of cancer of the neck of the uterus. The two other types (HPV 6 and HPV 11) are related to benign lesions called warts, which, although annoying, do not cause malignant lesions.

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As you contract the infection?

The HPV virus is transmitted with sexual intercourse, complete and not: it is a common infection, and it is estimated that worldwide more than 75% of women have been infected by the virus during their lifetime.

In the majority of cases the woman is not aware of it: in fact, in 3 cases out of 4 the infection is asymptomatic, that is; does not procure any trouble, and resolves, without treatment.

Instead, in 1 case out of 4 può cause benign lesions (warts), or other lesions which, if untreated, can lead to cancers of the uterine cervix. the From when you contract the infection when it develops, the cancer can take 20-30 years for the cancers that affect women of 45-50 years are the result of infections contracted at a young age.

How is the vaccination?

The vaccine is administered through an intramuscular injection. There are 3 doses: the second after 2 months and the third after 6 months from the first dose.

Perché vaccination is recommended at 12 years of age, if the tumor affects most adult women?

Becauseé it is a vaccine, and then has the purpose of preventing the infection, not to cure it.

Should be administered before the person is infected by the virus, a condition which occurs definitely before the first sexual intercourse. In fact, vaccination has the greatest efficacy in women who have not come into contact with the virus: the protective effect decreases considerably, if it is; già been in contact with one or more of the viral strains contained in the vaccine.

So for all the women who have alreadyà had sexual intercourse the weapon più effective and safe available to prevent cervical cancer is the Pap Test.

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What is the effectiveness of vaccination?

studies undertaken to date have involved women of age less than 26 years of age who had not been infected by the virus. In these women the vaccination is effective in preventing 98% of the cases of infection due to strains of HPV of the vaccine and the injury pre-cancerous related, that is; those that can precede the development of cancer. It also allows you to also prevent other injuries, condyloma, not related to the development of cancers.

it is critical to remember that vaccination is an important ally to reduce the risk of cancer, but alone is not enough. The vaccine, in fact, protects from benign lesions (condylomas), associated with two of the viral strains in the vaccine (HPV 6 and 11) and prevents injury to the pre-cancers associated with the two other strains in the vaccine (HPV 16 and 18), which constitute about 70% of the cases.

it Remains, therefore, a 30% of the cases that are not protected by vaccination and for this reason it is extremely important that in the future women, even if vaccinated before pubertà, and put them with regularityà Pap Test every 3 years.

can I make the vaccine if I have più 12 years old?

The vaccine può also be useful if you have more than 12 years, but its effectiveness decreases if you è già entered in contact with 1 or moreù of the viral strains contained in the vaccine itself. Therefore, its effectiveness is highest in women who have not had sexual relations.

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women who have had sexual relations may come into contact with the virus without realising it, from the moment the infection in 3 cases out of 4 not power of attorney any symptoms. Then for the latter, the only weapon proven to be very effective is the Pap Test every 3 years. Currently the vaccine is indicated in women with more than 26 years.

What are the side effects of the vaccination?

The studies carried out until now have shown that the vaccine is safe and the side effects of the più municipalities are represented by the irritation of the skin at the injection.

since the vaccine has been tested on a number of women, relatively small, until now it has been possible to identify any rare adverse reactions. Then, as with all medications newly placed on the market, it is essential to inform your physician of any side effects.

How long is the effectiveness of the vaccine?

The available data seem to indicate that the immunization offered by the vaccine lasts 5 years. At the moment do not have any other information: studies to determine the overall duration of the vaccination coverage are still ongoing, and only when they will be concluded sarà can know every how much time will be needed to the references.

Content freely adapted from SAPERIDOC, thank you for the courtesy.

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Page updated on April 1, 2007