> Paralyzed for 4 years, back to walk thanks to the cells of the nose

The surgeons of poland have used olfactory cells of the patient, Darek Fidyka, paralyzed for four years, to provide pathways along which the damaged tissue was able to grow.

The man, a Bulgarian of 38 years, is the first person in the world to recover from complete rupture of the spinal nerves, now può to walk with the aid of a frame, the sensitivityà and è returned to the lower limbs, and is able to resume an independent life, even to the point of driving a car.

professor Geoffrey Raisman, whose team at the Institute of University College London discovered the technique, said: “we Believe that this procedure is a breakthrough and, once developed, is tradurrà in a historical change of the current prospects and no hope for people disabled by spinal cord injury”.

The event è was performed by a Polish team led by one of the world’s top experts on repair of the vertebral column, Pawel Tabakow of the Wroclaw Medical University, who has  the transplanted cells in the olfactory lining of the nose (OECs) into the spinal cord.

The OECs may facilitate the repair of damaged nerves that transmit messages. Transplanted into the spinal cord, seem to allow the endà of the nerve fibres, cut to grow and join together. This is an event that you previously thought was impossible.

in Fact, while some patients with spinal injury partial have made remarkable recoveries, a complete break in general it was presumed that irreparable.

The research, financed by the Foundation of the Nicholls Spinal Injury (NSIF) and UK Stem Cell Foundation, has been made known in the course of a BBC programme.

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Raisman, who hopes to see at least three more patients treated in Poland over the next three to five years if funding reaches the necessary sum, has declared: “The patient is now able to move around the hips and on the left side and has in fact recorded a significant recovery of the muscles of the legs”.

Expressing satisfaction, Raisman has then told that Fidyka “può go around with a walker and has been able to resume much of his original life, including driving a car. Non può to dance, but è absolutely happy.”

The founder of the NSIF, David Nicholls, whose son Daniel was paralyzed since 2003, has explained that the information related to this breakthrough science will be made available to researchers all over the world.

Nicholls said that “paralysis is something that many of us do not know, becauseé I don’t have experience. One of the moments più devastating for a parent is to see their son or daughter lying motionless in bed and know that I can notà never to walk again.”

“The scientific information relating to this significant progress,” he added, Nicholls – will be made available to other researchers around the world so that together we can fight to finally find a cure for this condition which robs people of their lives.”

Raisman said that he never believed that the central nervous system is not able to regenerate connections in damaged. He added: “nerve fibers are trying to regenerate continuously. But there are two problems, the safety barriers, which are scars, and a great big hole in the path that they have to do. So thaté the nerve fibres to express that ability; they have always had to repair themselves, first the scar has to be open, then you must provide a channel that porterà where they need to go.”

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The scientist pointed out that thereò that è was made &is a leap forward beyond promoting “plasticità”, the rewiring of remaining connections.

The professor added: “The number of patients who are completely paralysed is enormous. There are millions all over the world. If we can convince the communityà scientific that this procedure works, then its development will be very più fast.”

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23 October 2014