> Diabetes: a positive test with the intelligent insulin that activates when you need it

According to a recent study there are high hopes that the insulins are “smart”, or Smart, which are in the course of the trial, will revolutionize the modeà – management of diabetes.

The support scientists of the Massachusetts Institute of Technology (Mit) in Boston, in an article published in the journal of the American Academy of Sciences (Pnas).

Instead of subjecting the patient to continuous blood tests and repeated injections during the day to keep her blood sugar under control, a single dose of intelligent insulin would keep circulating in the body and activate when there is needà.

For now, animal studies show that the technology seems to work, at least in laboratory rats, and scientists plan to move soon to human trials.

In the same article, the same experts warn altresì that it will take years of testing before treatments could become a reality for patients.

The experts who do studies on diabetes, from the time they are looking for ways to make the control of blood glucose levels in blood sugar più easy and more convenient for patients, and from this research were born the insulins are “smart”.

There are a few different types of insulins Smart in the phase of development, but all are designed to turn on automatically when the blood glucose becomes too high, and to switch off when you go back to normalityà.

Danny Chou, Massachusetts Institute of Technology, is testing for a long time, a intelligent insulin that he and his colleagues developed in the laboratory.

this Is a modified chemically capable of regulate the insulin prolonged action, which has a set of molecules stuck on the endà that bind to proteins circulating in the blood. While è linked to these, the intelligent insulin is in modeà off.

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When the sugar in the blood increases, the intelligent insulin activates and gets to work.

Chou explained: “my goal is to make life more easy and safe for diabetics, and this is an important step forward in insulin therapy”.
Richard Elliott of the organization, “Diabetes UK” has commented that “will take years of further research and clinical trials to find out if a similar drug could be used safely and effectively for people with diabetes”.

The expert added that “The data demonstrate that the insulin-modified, remains in the bloodstream for at least 10 hours, being able to intervene in a più fast and effective compared to insulin traditional and long duration of action, and this makes us optimistic about the future of these insulins Smart”.


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February 2013